What is psoriasis?

What is psoriasis On the basis of psoriasis is:
  • excessive reproduction of cells;
  • Abnormalities in the keratinocytes;
  • The appearance of inflammatory infiltrate in the dermis.
Speaking on the chronic nature, it should be noted that if the young man appeared a small stopper and soon disappeared — this means that in 20 years, you can again see the new panel. Psoriasis "snooze", but not curable, and its behavior resembles a man who many years ago "cured" of alcoholism, but apparently the reason is to prevent any alcohol, because after 30 years of sobriety to get in the match.

Causes of psoriasis

Causes of psoriasis The prevalence of psoriasis is very high: even in the prosperous countries of Western Europe, it is found in 2% of the population. For the beginning of the disease may at any age, but the debut often occurs at a young age, and only in 1/3 of patients, which occurs after 40 years. It is believed that the presence of family members with psoriasis, which significantly increases the risk for its occurrence, and there is autosomal dominant type of genetic failure (i.e., not related to Paul). But, most often, the causes of psoriasis are the effects of multiple adverse factors, which contribute to the changes in the body. A list of the most important causes of psoriasis:
  • Chronic stress, emotional stress, adverse social environment;
  • Microbial and viral infections, which are prone to chronicity, (e.g., steptokokkovaya infection );
  • Direct physical effects on the skin (excess friction, pressure, often insolation);
  • Lesions on the skin.
  • Hormonal imbalance. Psoriasis often occurs when they enter puberty, and rarely in menopausal women. This is due to the influence of the thyroid gland and hormones of the adrenal cortex;
  • Taking certain medicines. This effect was observed also in the lithium salts used in psychiatry, anti-treatment of malaria-chloroquine;
  • Alcohol, in particular beer. Also contributes as a more severe course of the disease, as well as basic, start;
  • Obesity or excess body weight. There are indisputable facts, which show that people who have brought their weight back to normal after years of surplus, the psoriasis has almost disappeared and even psoriatic arthritis
  • Climatic factors. Psoriasis takes place in the sea, the warm, Sunny climate. But continental, humid and cold climate can help both the beginning and progression of the disease;
  • Infection with the HIV virus. These diseases contribute to the emergence of different diseases, which "are" the failure of the immune system, and psoriasis is no exception.
What happens in the skin, or the pathogenesis of psoriasis in the pathogenesis of psoriasis One of the psoriasis is a skin plate, the resulting immune inflammatio, as well as in the joints, if psoriaticheskom arthritis. In blayshkah discovered a number of substances, for example, analogues of the leukotrienes that attract leukocytes into the centre of the inflammatio. The interaction of keratinocytes with immunokompetentnymi cells occur to the area of inflammatio, with the release of mediators of inflammatio. In psoriaticheskih blayshkah, and in the synovial fluid when present psoriaticheskom arthritis TNF-alpha, or tumor necrosis factor. The Tumor itself has nothing to do with — this name is historical. It is known that TNF is actively involved in various chronic inflammatio.
In the skin there are a variety of inflammatory changes that cause this is very typical for psoriasis triad of symptoms: spots, terminal protectors and a bloody dew.
  • With a light poskablivanii plate (e.g., a nail), is characterized by crushing and peeling of the scale.;
  • Under certain conditions (e.g. after the shower, have dry skin), you can pick up on the edge of the scales and removed in the form of a gray – yellow, like parchment, thin films, which sometimes reaches the area 3-4 cm cm is a symptom of terminal protectors;
  • If the site removed the movie poskoblit there is still the appearance of small drops of blood as rosa, which is called blood.
This may cause the skin itching at night, the patient stryahivaet leaves with a lot of dead skin flakes which resemble a mixture of flour with the bran, and the leaves can drops of blood. Symptoms characteristic of the acute stage.

Psoriasis — initial phase photos

Psoriasis panel affect all layers of the skin. In psoriasis, initial stages of plaque after full development, does not differ in its main features from the usual panels, but in the beginning it has the following features:
  • is formed on the surface of the skin flat bump, having a diameter of 1-3 mm;
  • its clear limits;
  • colour: dark red or pink, occasionally blue, especially on the psoriasis on the feet;
  • the surface becomes friable, which is formed by layers of flakes, with silver-white color;
  • panels merge, the result is a large rash.
With the emergence of Kebnera or primary damage to the skin and is often starts psoriasis. If localized rashes? Symptoms of early stages of psoriasis can be seen in the "favorite places." These include:
  • The surface of the elbow and knee joints (and sometimes the back, this is called "inverse psoriasis");
  • The sacrum;
  • Volosennaya head. Lifting the hair, you can see the edge of the red rim of the skin at the time of the aggravation, slightly protruding beyond the line of hair growth: "psoriaticheskuyu the crown";
  • Psoriasis "loves" to live behind the ears near the hair growth, and inside the ears;
  • Some of the less often affects larger skin folds.
In some cases, the development of the panels contributes to severe itching. Often this along with skin redness on the outskirts of said progressive stage of psoriasis, when new scales.

Psoriasis on the nails of the feet and hands (+ photo

Nail psoriasis, affects almost 50% of patients. Shown are the pits and dots. Its free edge is always bad, it is yellowish that can raise suspicion for fungal disease. The body of the nail changes color, it seems as if a transparent area, which is called "oil."
Most often, the loss of the nails show that the patient has psoriatic arthritis, or have a tendency to develop.
Will suffer from psoriasis can not all nails, but only on the legs or hands. And even if the arthritis on the fingers, the fingernail on the hand, will not necessarily be struck precisely where the pain in the joints. May be damaged by small fingers, and index fingers hurt. There is no direct link.

Phase of psoriasis — the acute, stability, and regression

All the trouble and sorrow are in the progression of the disease, when the acute symptoms. In each patient deterioration has individual character. Sometimes cause deterioration in response to the "good purpose". For example, the patient many years of Smoking. Deciding that Smoking is harmful impact on psoriasis (and rightly so), he throws, but after a month adds up to 5-8 kg. the result is a significant increase, which appeared on the body weight and "ignored" the fact that a successful fight against Smoking. The deterioration of the Despite the "special way", there are some common signs:
  • The deterioration appears, when cold, sore throat, stress, binge;
  • There is the emergence of new spots;
  • To the old spots expanded, the peripheral area, spot "grows";
  • A thick layer of scales;
  • Increases the itching. In the room where there lives the patient with psoriasis, it is better to put laminate flooring and linoleum, as they are less visible skin flakes that appear in large numbers after the itching of the panels;
  • In severe forms of increased pain in the joints, there is a General malaise;
  • For progressive stage characterized by the emergence of Kebnera. All of the lesions on the skin changing in the new panels.
A stable state Reducing the signs of aggravation of psoriasis — plaques are not changed, in particular, the itching happens. The "shell" of the patient spilling a little. On blayshkah stop the growth, "psevdoartoficheskyi" panel, which can disappear and re-occur deterioration. Regression Most often, the improvement starts from the center of the plaque. There begins the disappearance of the scales, is a new skin. The peripheral area of the growth is pale and inactive, the result is a "garland" rings and all sorts of bizarre places. If the rash has disappeared completely, it is often at this point is a patch of skin with reduced pigmentation. Very often regress psoriaticheskih rash develops in the summer months, when the patient is in the sun. Aggravation, in contrast, occur in spring and autumn, when the skin suffers from a lack of sunlight.
  • When a partial regression of the lesions often remain "on-duty plates", which are localized in the region of the elbows and knees.

Types of psoriasis, especially on the skin,

Types of psoriasis The ordinary, skin psoriasis, there are several types: seborrheic, exudative psoriasis, skin folds, palms and soles. Nail psoriasis does not usually occur separately.
  • Seborrheic form is very similar to dermatitis. Scales localized on the scalp, behind the ears, on the chest. For injuries that are diffuse boundaries, are impregnated with cutaneous fat and the fat, thick and loose scales;
  • In exudative psoriasis (which is more common in obesity) fluid, which impregnates the flakes, a small change in the symptoms. In the result, the scales lose their silvery color, glued, and similar becomes a yellow crust;
  • Psoriasis in palms and soles, which is more common in persons who perform physical work (chronic injury), sometimes the rash is isolated. Often develops hyperkeratosis, ;
  • Psoriasis skin folds mainly developed, with strong pathology for example, diabetes. Plates appear around the navel, under the Breasts, perineum and inguinal folds.
Sometimes psoriaticheskie the rashes appear on the genitals. In this case, if you are only a symptom of the disease and psoriasis the body is not, then there are certain difficulties in the differential diagnosis of psoriasis, and urogenital infections. Severe psoriasis Familiarize yourself briefly with the generalizovannimi forms of psoriasis is psoriaticheskaya aritrodermiya , pustuleznyi psoriasis and arthritis.
  • psoriaticheskaya aritrodermiya is nothing like the progressive stage of psoriasis, exciting the entire skin.
The skin becomes hot, the overall temperature rises to high numbers. On the basis of the General aritrodermii, not to see the pattern of previous psoriasis: everything is combined in one joint inflammatio. This condition can cause aletrolitnye disease and heart failure.
  • When Pustuleznom psoriasis is characterized by the appearance of pustules, or ulcers.
These ulcers are at first sterile, and are composed of neutrophils, but may then become infected. The disease is also severe, with signs of inflammatio, a burning sensation and pain on the skin, common reactions, changes in blood, increased ESR. Pustules fuse together and appear purulent "the lake". Pustules are in different stages of development, and may also develop serious complications (kidney and heart).
  • Psoriatic arthritis pain, often in hands and feet.
Sometimes pandaktilit – finger inflammatio, which resembles a "sausage", the skin on it has a bluish tint. As a rule, for the first time, that lesions on the skin, and then in the affected joints. Also affect the joints, spine, temporo – mandibular joint.
Involvement of the joints in the axial skeleton suggests unfavorable course of the disease. In severe cases, the end-phalanges are completely destroyed and the mutiliruyushaya form of psoriasis.

Psoriasis treatment drugs, ointments and treatment methods

To firmly remember: complete healing of psoriasis is not possible, and a universal cure for psoriasis does not exist. However, you can gain the permanent life of the remission, normal health status, and the complete absence of panels.