Ointment psoriasis - what is the more effective ointment for psoriasis?

People living with a diagnosis of "psoriasis" I know from first hand how much depends on the correct choice of medicines. This disease does not forgive errors in the treatment and the negligent attitude to their health. An important role in controlling the symptoms of psoriasis to play a well-chosen external therapy and timely treatment. A key principle in the selection of treatment regimens, especially in the early stages of psoriasis development, is the principle of "do no harm" treatment may not strike at the health of the skin, provoking the emergence of unwanted consequences in the form of skin atrophy or syndrome. After all, the primary goal of therapy is to prolong the rest and health of the skin, without a sudden and painful relapses and exacerbations.

ointment psoriasis

Hormonal ointments for psoriasis: cure or kill?

Group external remedies for treatment of psoriasis are ointments on the basis of specific hormones. These substances have the property to inhibit the activity of the immune system, reduce inflammation. Therefore, in severe exacerbations of psoriasis steroids gives the system, such as pills or injections. However, this approach is fraught with serious side effects: therapy changes the hormonal balance in the body, and the withdrawal of the medication can lead to disruption in the functioning of the endocrine and cardiovascular system.

Topical steroids (external hormonal) are partly without the hazardous properties of the system of the medicinal product on the basis of the hormone: the effect is manifested only at the point of use. Their advantage is speed of operation: a few minutes after application, patients notice a reduction of pruritus, and in the next few days, significantly reduced the redness of the psoriatic plates, stops your growth, and exfoliation.

Unfortunately, the side effects typical to topical steroids — and no less serious: because of low resistance at the point of use, the skin becomes thinner and discolored, there is a risk of secondary infection. This, without doubt, makes it difficult to treat. The most serious consequence of the use of topical steroids is the development of addiction. As a result, other products (even the topical steroids) already stopped to help, causing another, sometimes much more severe relapse after discontinuation of the drug. This is the reason, why the sale of topical steroids in Europe and the United states without a prescription is prohibited. The independent and uncontrolled use of these resources, which are related to the category of strong, unacceptable.

It is important that you know! Addison's disease — a disease that develops due to long-term medications, corticosteroids. In response to the hormone treatment only the adrenal glands cease to produce cortisol and other steroids, which is reflected by symptoms such as muscle weakness, loss of weight and appetite, lowering blood pressure, dehydration, heart palpitations and constant voltage. In Addison's disease the doctors are not always able to restore adrenal function, so that patients life prescribed hormonal therapy.

Most of the funds on the basis of topical steroids is inexpensive and sold without prescription, so the cases of abuse of this type of psoriasis are common. Meanwhile, dermatologists do not recommend the use of local steroids is extensive (more than 20% of the surface of the skin) the areas of injury, and that the use of these funds for the sensitive parts of the body — face, neck, skin folds and diaper rashes. It is desirable to completely abandon the idea to use hormonal ointments and creams without a prescription: it is able to reduce the effect of the primary treatment, harm to health and provoke an attack of severe exacerbation of psoriasis.

The most common hormonal creams and ointments are made on the basis of the following substances:

  • betamethasone;
  • hydrocortisone;
  • mometasone;
  • methylprednisolone;
  • triamcinolone;

Normal non-hormonal ointments for the treatment of psoriasis: will not be worse, but better?

Due to the serious side effects of hormone creams and ointments, many patients prefer to treat psoriasis with a less "aggressive" medication. Some of them are the heritage of folk medicine and traditional recipes for skin care, popular in the past.

The advantages of the traditional non-hormone treatment of psoriasis is to be attributed its comparative with hormonal products, safety, cheapness, and lack of serious side effects. Disadvantages of the different (often low) degree of efficiency and, in some cases, allergic reactions that develop in patients to the components means.

signs of psoriasis
  • Naftalan, Ichthyol, dermatological-based grease, tar, — anti-inflammatory and antiseptic. However, some of them cannot be used in the progressive stage of psoriasis, and a large surface area injuries, while others (for example, coal tar ointment) have a certain impact, so they are not recommended to be combined with phototherapy. In addition, prolonged use of these drugs increases the likelihood of developing skin cancer. Traditional ointments have a strong smell and can stain clothing, therefore they are not very comfortable to use.
  • Specific substances that have anti-inflammatory and anti-microbial function and cause increased exfoliation of dead skin cells, which accelerates the process of treatment for the psoriatic plates. Among the possible side effects — the risk of inflammatory reactions, burning and pigmentation of the surrounding healthy skin (discoloration of healthy skin and hair in brown color).
  • Herbal (ointments and creams based on aloe, elecampane, celandine, sage and other herbs) have anti-inflammatory and healing effects, to help prevent the development of skin infections. Aided in the treatment of psoriasis, which is complementary to the effect of the primary treatment.
  • Moisturizers (creams and baby oils, cosmetics) are also auxiliary in the treatment of psoriasis and helps in the fight against skin dryness and feeling of tightness of the skin. They are used in combination with medications to increase the effect of therapy.

Non-hormonal creams and ointments, with a pronounced therapeutic effect: the clinically proven

Also, we point out a group of non-hormonal drugs, whose effectiveness in the local treatment of psoriasis has been confirmed in clinical trials. Unlike ointments and creams of the previous groups, the mechanism of action of these drugs is studied in detail. Have indisputable advantage before hormonal products in conjunction with a greater safety profile. However, in the treatment of these assets should be clear, to follow the instructions for use and be aware of possible contraindications.

  • Pimecrolimus has high anti-inflammatory activity. However, it is important to note that in the case of bacterial or fungal skin the use of funds on the basis of pimecrolimus is recommended only after a cure for the infection. The uncontrolled use of pimecrolimus may cause local immunosuppression in the skin (local suppression of the immune system), which increases the risk of joining a secondary infection on the affected areas of the skin. So, in the united states, for example, pimecrolimus is recommended only as a cure "second-line" treatment, which is not only in the absence of effect from other treatment methods. Pimecrolimus is prohibited for use for children up to two years.
  • In the calcipotriol is a synthetic analogue of vitamin D3. Its operation is based on the increase in the level of calcium in the skin cells, normalizes the rate of their division and promotes the resorption of psoriatic plates. Due to calcipotriol is a hormonal medication (that is, after a series of biochemical reactions, which is converted to the active hormonal metabolite calcium metabolism), there are a number of restrictions on its use. In particular, the calcipotriol does not apply, if you are losing more than 30% of the surface of the skin because of the risk of hypercalcemia. The latter can cause irregular heartbeat and muscle spasms. It is not advisable to use calcipotriol on the sensitive parts of the skin (face, neck, wrinkles). Means, on the basis of these active substances, which have age restrictions. Of calcipotriol is also not suitable as auxiliary means, in the case of the treatment of phototherapy, because under the influence of UV light, which causes sensitivity to light and lead to the development of a skin burn.
  • In the zinc pyrithione. Due to the proven efficacy and safety of the treatment, medicines for the treatment of psoriasis on the basis of these active substances, which can be attributed to the categories of "the Golden mean". Zinc is a organic and natural cure for the treatment of skin diseases. Its concentration in healthy human epithelium is about 20% of the total content in the body, and deficiency of this precious metal accompanied by different lesions on the skin and impaired wound healing. Drugs with the active zinc (zinc pyrithione) have a whole range of special properties (anti-inflammatory, antibacterial, antifungal), to help reduce itching, promote the development of ceramides (lipids) in the skin, which leads to the restoration of its barrier function. Tools zinc pyrithione activate the so-called apoptosis (natural, programmed death) pathologically changed skin cells and cells of inflammation and, thereby, activates the natural renewal of skin cells, decreasing scaling and elimination of the psoriatic plates. Studies have shown that the active zinc has a comparable hormonal products effectiveness and good safety profile, as it is practically not absorbed from the skin, which is not disturbing and harmful effect.

Ointment or cream?

Many of these drugs are produced in the form of ointments and cream. How to choose the most appropriate form?

  • Ointments are more dense and oily texture, which allows the drug to be a long time on the surface of the skin, especially if you put it under the bandage.
  • The cream has a soft texture, easier to use and absorbs quickly so that it can be used, leaving the skin open, not with bandages, and not being afraid to stain clothing or hands. Usually, the cream has a pleasant smell, which is also important for daily use.
  • Unlike an ointment, a cream, and to a lesser extent irritation, so it is most suitable for use on the face, the flexion of the joints, in areas with a high degree of sensitivity. Also grease is not suitable for application on moist areas of the affected skin with liquid discharge. The cream is in this sense more universal.
  • Traditionally, the ointment of psoriasis, represents the general, however, this imbalance gradually disappears — the market appears more and more new pharmaceutical forms, in the form of creams, gels, and aerosols, which are suitable for use and especially suitable for use in inaccessible areas (e.g. the scalp).
treatment of psoriasis

Looking for a balance of price and quality

Let's try to summarize the data in a table:

Group drug

The active ingredients

Action

The potential limitations and side effects

Hormonal creams and ointments

Betamethasone

They have anti-inflammatory, anti-allergic (including anti-itching) and anti-edematous action. Hydrocortisone, methylprednisolone and other tools, also have a certain measures (large local resistance of the skin).

1. It is not recommended for use long-term (more than 5 days) and often. 2. Can trigger the development of local complications:

  • discoloration and metabolic disorders in the skin;
  • syndrome;
  • the immunosuppressive effect can lead to the accession of secondary infection on the skin.
  • Contraindicated:
  • for use in areas with sensitive skin (face, neck, wrinkles);
  • when large areas of the lesions (more than 30% of the skin).

Mometasone

Hydrocortisone

Glucocorticoid remedy

Methylprednisolone

Triamcinolone

Non-hormonal traditional means

  • Oil
  • Sulphur
  • Ichthyol
  • Fat
  • Tar

They have anti-inflammatory and antiseptic.

  • They are fairly low efficiency and does not affect the bacterial and fungal agents (when joining a secondary infection of the skin).
  • Frustrating to use (used several times a day, often under the bandage, require very long-term treatment, stain clothing and have unpleasant odour).
  • Can cause irritation and dry skin, and allergic reactions.

A substance which causes the active exfoliation of dead cells from the surface of the skin:

  • dithranol
  • sulfur and salicylic acid

Cause increased exfoliation of dead skin cells, have anti-inflammatory and antimicrobial action.

Can cause an inflammatory reaction, burning and pigmentation of the surrounding healthy skin (discoloration of healthy skin and hair in brown color).

Non-hormonal drugs

Pimecrolimus

It has anti-inflammatory activities.

  • Not recommended in case of bacterial or fungal infections of the skin.
  • Can cause local immunosuppression of the skin (reduction of local immunity).
  • Contraindicated in children up to two years.

Of calcipotriol

Is a synthetic analogue of vitamin D3, promotes the resorption of psoriatic plates.

  • We do not recommend:
  • if you want to use, if you are losing more than 30% of the surface of the skin because of the risk of hypercalcemia;
  • apply to sensitive skin areas (face, neck, wrinkles, scalp);
  • in combination with the method of phototherapy in conjunction with the risk of receiving skin burns.
  • Contraindicated in patients under the age of six.

Zinc pyrithione

Has a complex action:

  • anti-inflammatory;
  • antipruritic;
  • protection against infection;
  • activating the natural renewal of cells of the epithelium for the elimination of the psoriatic plates;
  • the restoration of the barrier function of the skin.
  • It has a high safety profile.
  • No restrictions on duration of use and scope.
  • No side effects (except individual intolerance).
  • Approved for use child for one year.

Psoriasis is a chronic disease so each patient, it is important to find the best remedy that combines high efficiency and low side effects (and preferably at a reasonable price). And don't forget: before you start using any tool, read the instructions, all the possible contraindications and side effects, and also be sure to check with your doctor. This will help to achieve the best results without injury.

ointment against psoriasis

Early treatment of psoriasis is a key success factor. Don't forget that the sooner you begin to treat psoriasis, it is less likely that you will ever have to resort to "heavy artillery" — hormonal means.

04.10.2018